| Pre | | Cleethorpes Town | Tue 04/07/2017 | 19:00 | Bradley | 4‑2 | 1,200 | | |
| Pre | | Grimsby Borough | Thu 06/07/2017 | 19:00 | Bradley | 11‑3 | 1,000 | | |
| Pre | | Stamford A.F.C. | Tue 11/07/2017 | 19:30 | Vic Couzens Stadium | 3‑2 | 268 | | |
| Pre | | Scunthorpe | Thu 13/07/2017 | 19:30 | Blundell Park | 4‑0 | | | |
| Pre | | Barnsley | Sat 15/07/2017 | 13:30 | Blundell Park | 2‑1 | 1,903 | | |
| Pre | | Bideford AFC | Tue 18/07/2017 | 20:30 | The Sports Ground | 4‑0 | | | |
| Pre | | Tavistock AFC | Thu 20/07/2017 | 20:30 | Tavistock AFC | 7‑1 | | | |
| Pre | | Boston United | Sat 22/07/2017 | 15:00 | York Street | 0‑3 | 677 | | |
| Pre | | Blackburn Rovers | Tue 25/07/2017 | 19:30 | Blundell Park | 0‑1 | 1,692 | | |
| Pre | | Winterton Rangers | Thu 27/07/2017 | 19:30 | West Street | 7‑0 | | | |
| Pre | | Wigan Athletic | Sat 29/07/2017 | 15:00 | Blundell Park | 1‑1 | | | |
| League | | Chesterfield | Sat 05/08/2017 | 15:00 | Proact Stadium | 3‑1 | 7,925 | Report | Thread |
| League | | Coventry | Sat 12/08/2017 | 15:00 | Blundell Park | 0‑2 | 6,767 | Report | Thread |
| League | | Stevenage | Sat 19/08/2017 | 15:00 | Broadhall Way | 1‑3 | 2,793 | Report | Thread |
| EFLC | 1 | Derby | Tue 22/08/2017 | 19:45 | Blundell Park | 0‑1 | 3,033 | | Thread |
| League | | Wycombe | Sat 26/08/2017 | 15:00 | Blundell Park | 2‑3 | 4,016 | Report | Thread |
| EFLT | 1A | Doncaster | Tue 29/08/2017 | 19:45 | Blundell Park | 1‑1 (3‑4p) | 862 | | |
| League | | Crewe | Sat 02/09/2017 | 15:00 | Blundell Park | 1‑0 | 4,066 | Report | Thread |
| League | | Mansfield | Sat 09/09/2017 | 13:00 | Field Mill | 1‑4 | 4,625 | Report | Thread |
| League | | Accrington Stanley | Tue 12/09/2017 | 19:45 | Crown Ground | 2‑1 | 1,288 | Report | Thread |
| League | | Yeovil | Sat 16/09/2017 | 15:00 | Blundell Park | 2‑1 | 3,945 | Report | Thread |
| League | | Newport County | Sat 23/09/2017 | 15:00 | Newport Stadium | 0‑1 | 3,356 | Report | Thread |
| League | | Colchester | Tue 26/09/2017 | 19:45 | Blundell Park | 2‑2 | 3,438 | Report | Thread |
| League | | Lincoln City | Sat 30/09/2017 | 13:00 | Blundell Park | 0‑0 | 7,669 | Report | Thread |
| EFLT | 1B | Scunthorpe | Tue 03/10/2017 | 19:45 | Glanford Park | 1‑2 | 1,987 | | |
| League | | Port Vale | Sat 07/10/2017 | 15:00 | Vale Park | 2‑1 | 5,849 | Report | Thread |
| League | | Crawley Town | Sat 14/10/2017 | 15:00 | Blundell Park | 0‑0 | 4,007 | Report | Thread |
| League | | Cheltenham | Tue 17/10/2017 | 19:45 | Whaddon Road | 3‑2 | 2,469 | Report | Thread |
| League | | Morecambe | Sat 21/10/2017 | 15:00 | Globe Arena | 0‑0 | 1,525 | Report | Thread |
| League | | Cambridge Utd | Sat 28/10/2017 | 15:00 | Blundell Park | 0‑0 | 4,091 | Report | Thread |
| FAC | 1 | Plymouth | Sat 04/11/2017 | 15:00 | Home Park | 0‑1 | 5,137 | | |
| EFLT | 1C | Sunderland | Wed 08/11/2017 | 19:45 | Blundell Park | 1‑1 (6‑7p) | 248 | | Thread |
| League | | Exeter | Sat 11/11/2017 | 15:00 | St James Park | 0‑2 | 3,854 | Report | Thread |
| League | | Carlisle | Sat 18/11/2017 | 15:00 | Blundell Park | 0‑1 | 3,753 | Report | Thread |
| League | | Swindon | Tue 21/11/2017 | 19:45 | Blundell Park | 3‑2 | 3,023 | Report | Thread |
| League | | Barnet | Sat 25/11/2017 | 15:00 | The Hive | 2‑0 | 2,033 | Report | Thread |
| League | | Forest Green | Sat 09/12/2017 | 15:00 | Blundell Park | 1‑0 | 4,398 | Report | Thread |
| League | | Notts County | Sat 16/12/2017 | 15:00 | Meadow Lane | 0‑0 | 8,016 | Report | Thread |
| League | | Luton | Sat 23/12/2017 | 15:00 | Kenilworth Road | 0‑2 | 9,102 | Report | Thread |
| League | | Mansfield | Tue 26/12/2017 | 13:00 | Blundell Park | 1‑1 | 5,704 | Report | Thread |
| League | | Accrington Stanley | Sat 30/12/2017 | 15:00 | Blundell Park | 0‑3 | 4,188 | Report | Thread |
| League | | Crewe | Mon 01/01/2018 | 15:00 | Gresty Road | 0‑2 | 3,292 | Report | Thread |
| League | | Morecambe | Sat 06/01/2018 | 15:00 | Blundell Park | 0‑2 | 3,104 | Report | Thread |
| League | | Newport County | Sat 13/01/2018 | 15:00 | Blundell Park | 1‑2 | 3,397 | Report | Thread |
| League | | Colchester | Sat 20/01/2018 | 15:00 | Weston Homes | 1‑1 | 3,016 | Report | Thread |
| League | | Luton | Sat 27/01/2018 | 15:00 | Blundell Park | 0‑1 | 4,159 | Report | Thread |
| League | | Yeovil | Tue 30/01/2018 | 19:45 | Huish Park | 0‑3 | 2,330 | Report | Thread |
| League | | Cheltenham | Sat 03/02/2018 | 15:00 | Blundell Park | 1‑1 | 3,352 | Report | Thread |
| League | | Crawley Town | Sat 10/02/2018 | 15:00 | Broadfield Stadium | 0‑3 | 2,055 | Report | Thread |
| League | | Cambridge Utd | Sat 17/02/2018 | 15:00 | Abbey Stadium | 1‑3 | 4,739 | Report | Thread |
| League | | Exeter | Sat 24/02/2018 | 15:00 | Blundell Park | 0‑1 | 4,151 | Report | Thread |
| League | | Carlisle | Sat 03/03/2018 | 15:00 | Brunton Park | 0‑2 | 4,151 | Report | Thread |
| League | | Port Vale | Sat 10/03/2018 | 15:00 | Blundell Park | 1‑1 | 5,198 | Report | Thread |
| League | | Lincoln City | Sat 17/03/2018 | 13:00 | Sincil Bank | 1‑3 | 9,774 | Report | Thread |
| League | | Coventry | Sat 24/03/2018 | 15:00 | Ricoh Arena | 0‑4 | 8,755 | Report | Thread |
| League | | Stevenage | Fri 30/03/2018 | 15:00 | Blundell Park | 0‑0 | 5,368 | Report | Thread |
| League | | Wycombe | Mon 02/04/2018 | 15:00 | Adams Park | 1‑2 | 5,215 | Report | Thread |
| League | | Chesterfield | Sat 07/04/2018 | 15:00 | Blundell Park | 1‑0 | 6,780 | Report | Thread |
| League | | Barnet | Sat 14/04/2018 | 15:00 | Blundell Park | 2‑2 | 5,416 | Report | Thread |
| League | | Swindon | Sat 21/04/2018 | 15:00 | County Ground | – | | | |
| League | | Notts County | Sat 28/04/2018 | 15:00 | Blundell Park | – | | | |
| League | | Forest Green | Sat 05/05/2018 | 15:00 | The Lawn | – | | | |
Last Year's Results|
All League Two Fixtures
